| | Day | Time | | Opponent | Score | |
| November |
| | 1 | 2:00PM | @ | Union University | L-50-116 | |
| | 7 | 6:00PM | @ | Bethel College | L-66-91 | |
| | Bethel Tournament |
| | 8 | 12:00PM | vs. | Martin Methodist | L-60-99 | |
| | Bethel Tournament |
| | 15 | 1:00PM | @ | Freed-Hardeman | L-55-104 | |
| | 21 | 5:30PM | vs. | Calumet College of St. Joseph | W-59-55 | |
| | UIS Tournament |
| | 22 | 2:00PM | vs. | Avila University | L-69-106 | |
| | UIS Tournament |
| December |
| | 1 | 5:00PM | vs. | Southern Arkansas | L-63-74 | |
| | Henderson State Tournament |
| | 2 | 6:00PM | vs. | Henderson State | L-50-116 | |
| | Henderson State Tournament |
| | 20 | 5:30PM | @ | Emporia State University | L-35-119 | |
| | 27 | | vs. | TBA | L-0-2 | |
| | Saint Xavier Tournament Dec. 27-29 |
| | 28 | | vs. | TBA | L-0-2 | |
| | Saint Xavier Tournament Dec. 27-29 |
| | 29 | | vs. | TBA | L-0-2 | |
| | Saint Xavier Tournament Dec. 27-29 |
| January |
| * | 8 | 5:30PM | vs. | Missouri Baptist | L-69-77 | |
| * | 10 | 2:00PM | @ | University of Illinois at Springfield | W-64-59 | |
| * | 14 | 5:30PM | @ | Missouri Baptist | | |
| * | 15 | 5:30PM | vs. | McKendree | L-41-76 | |
| * | 17 | 2:00PM | @ | William Woods | L-67-86 | |
| * | 20 | 5:30PM | @ | Williams Baptist | W-73-70 | |
| * | 24 | 2:00PM | @ | Stephens | W-63-53 | |
| * | 29 | 5:30PM | vs. | Columbia | L-58-76 | |
| * | 31 | 2:00PM | vs. | Hannibal-LaGrange | L-62-65 | |
| February |
| | 4 | 7:00PM | @ | Southeast Missouri State University | L-45-73 | |
| * | 5 | 5:30PM | @ | Missouri Baptist | W-82-76 | |
| * | 7 | 2:00PM | vs. | University of Illinois at Springfield | L-57-63 | |
| * | 11 | 5:30PM | vs. | Missouri Baptist | | |
| * | 12 | 5:30PM | @ | McKendree | L-50-79 | |
| * | 14 | 2:00PM | vs. | William Woods | L-55-76 | |
| * | 17 | 5:30PM | vs. | Williams Baptist | L-75-82 | |
| * | 21 | 2:00PM | vs. | Stephens | W-88-68 | |
| * | 26 | 5:30PM | @ | Columbia | L-80-83 | |
| * | 28 | 2:00PM | @ | Hannibal-LaGrange | L-50-66 | |
| March |
| | 2 | 7:00PM | vs. | Stephens | W-70-57 | |
| | AMC Women's Basketball Tournament -- Opening Round |
| | 4 | 7:00PM | @ | William Woods | L-53-72 | |
| | AMC Women's Basketball Tournament -- Quarterfinal Round |
