| | Day | Time | | Opponent | Score | |
| February |
| | 27 | 1:00PM | @ | Evangel University | W-11-7 | |
| | Evangel Tournament |
| | | 3:00PM | vs. | Kansas Wesleyan University | W-11-3 | |
| | Evangel Tournament |
| | | 6:00PM | vs. | Rogers State University | L-3-4 | |
| | Evangel Tournament |
| March |
| | 4 | 2:00PM | @ | Quincy University | L-1-7 | |
| | | Game 2 | @ | Quincy University | L-0-3 | |
| | 8 | 12:00PM | vs. | University of Pittsburgh-Bradford | W-5-2 | |
| | | 7:00PM | vs. | Grand Valley State | L-1-2 | |
| | 9 | | vs. | Penn State Abington | W-12-0 | |
| | | 3:00PM | vs. | Penn State Behrend College | W-11-3 | |
| | 10 | 10:00AM | vs. | Ohio Valley College | W-4-1 | |
| | | 5:00PM | vs. | West Liberty State | L-0-4 | |
| | 12 | 11:30AM | vs. | Assumption College | L-2-3 (9) | |
| | | 7:30PM | vs. | Missouri Baptist | L-1-11 | |
| | 13 | 1:30PM | vs. | Simmons College | W-3-1 | |
| | | 5:30PM | vs. | Webber International | L-4-7 | |
| | | Game 2 | vs. | Webber International | L-0-6 | |
| * | 16 | 2:00PM | vs. | Williams Baptist | L-2-9 | |
| * | | Game 2 | vs. | Williams Baptist | W-7-4 | |
| * | 17 | 2:00PM | @ | Missouri Baptist | L-4-5 | |
| * | | Game 2 | @ | Missouri Baptist | W-3-2 | |
| | 21 | 1:00PM | vs. | Southwestern College | W-4-3 | |
| | | 5:00PM | vs. | Saint Gregory's University | L-0-9 | |
| | | 7:00PM | vs. | Peru State College | L-1-9 | |
| | 22 | 11:00AM | vs. | Avila University | W-9-1 | |
| | | 3:00PM | vs. | Baker University | W-9-4 | |
| * | 26 | 2:00PM | vs. | Harris-Stowe | W-6-5 (8) | |
| * | | Game 2 | vs. | Harris-Stowe | L-0-9 | |
| * | 31 | 2:00PM | @ | Columbia | L-0-7 | |
| * | | Game 2 | @ | Columbia | L-0-8 (5) | |
| April |
| * | 3 | 2:00PM | vs. | William Woods | L-3-6 | |
| * | | Game 2 | vs. | William Woods | L-1-2 | |
| | 6 | 2:00PM | vs. | Ashford University | RAIN | |
| | | Game 2 | vs. | Ashford University | RAIN | |
| | 7 | 3:00PM | vs. | Greenville College | W-6-2 | |
| | | Game 2 | vs. | Greenville College | W-2-1 | |
| | 10 | 12:00PM | vs. | Trinity International University | W-11-2 | |
| | | 2:15PM | vs. | Iowa Wesleyan College | L-1-2 | |
| | | 5:30PM | vs. | Purdue University-North Central | L-4-12 | |
| | 11 | 9:00AM | vs. | Judson College | W-7-0 | |
| | | 12:15PM | vs. | University of Saint Francis | W-4-1 | |
| * | 15 | 2:00PM | vs. | McKendree | L-3-4 | |
| * | | Game 2 | vs. | McKendree | L-0-1 | |
| * | 16 | 2:00PM | vs. | University of Illinois at Springfield | W-3-2 | |
| * | | Game 2 | vs. | University of Illinois at Springfield | W-2-0 | |
| | 18 | 12:00PM | vs. | University of Saint Francis | L-1-6 | |
| | | 4:00PM | vs. | Calumet College of St. Joseph | L-0-4 | |
| | 22 | 4:00PM | @ | Culver-Stockton College | L-3-4 | |
| | | Game 2 | @ | Culver-Stockton College | L-0-4 | |
| * | 24 | 3:00PM | @ | Stephens | W-7-1 | |
| * | | 5:00PM | @ | Stephens | W-4-2 | |
| May |
| | 1 | 12:00PM | vs. | Columbia | L-0-8 (6) | |
| | 2009 AMC Softball Tournament -- First Round |
| | 2 | 11:00AM | vs. | McKendree | L-6-7 | |
| | AMC Tournament at William Woods University |
